Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. GRPR
  3. mProX™ Human GRPR Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP GPCR Cell Lines,Drug Discovery Tools
    Family stable cell lines Bombesin Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human GRPR Stable Cell Line

    [CAT#: S01YF-0923-PY22]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Protein
    GRPR
    Target Family
    Bombesin Family
    Target Protein Species
    Human
    Host Cell Type
    A549;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Agoraphobia;Gastrinoma
    Gene ID
    Human: 2925
    UniProt ID
    Human: P30550

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The Gastrin-Releasing Peptide Receptor (GRPR) has emerged as a significant target in scientific research, particularly in the realm of oncology. GRPR's role in prostate cancer has been highlighted in studies such as the synthesis and evaluation of radio-iodinated GRPR/PSMA bispecific heterodimers, which are seen as promising agents for theranostics applications in prostate cancer. Additionally, the development of GRPR-targeting radiopharmaceuticals, especially for targeted radioligand therapy application, has been underscored due to the low pancreas uptake of its derivatives. Furthermore, the potential of GRPR in the surgical removal of GRPR-positive tumors has been demonstrated through the development of dual-modality probes for nuclear and fluorescence imaging. Clinical studies of radioactive GRP analogues suggest promising opportunities for both diagnostic tumor imaging and radiotherapy of GRPR-expressing cancers. In essence, the application of GRPR in scientific research is vast, with its potential in diagnostics, therapeutics, and surgical interventions being actively explored.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GRPR Stable Cell Line (S01YF-0923-PY22). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Anthony (Verified Customer)

    Is GRPR expression limited to the spinal cord? May 08 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    No, GRPR is expressed in various tissues and plays diverse roles, including in the progression of prostate cancer and other urological cancers. May 08 2023

    chat Linda (Verified Customer)

    Are there standardized criteria for interpreting GRPR-targeted PET? Apr 21 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, modified PROMISE criteria have been proposed to aid clinicians in evaluating, reporting, and comparing GRPR-targeted PET. Apr 21 2020

    Related Products by Target
    • Magic™ mPro Human GRPR Cell Line (CAT#: S01YF-1122-KX13)
    • Magic™ Human GRPR CHO-K1 Cell Line, Binding and Functional Assay (CAT#: S01YF-1222-KX361)
    • Magic™ Human GRPR CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay (CAT#: S01YF-1222-KX66)
    • Magic™ Human GRPR CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay (CAT#: S01YF-1222-KX360)
    • Magic™ Human GRPR CHO-K1 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX26)
    • mProX™ Human GRPR Stable Cell Line (CAT#: S01YF-0923-PY22)
    • Magic™ Human FLAG tagged GRPR HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX212)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare