GRPR
GRP, a potent mitogen for neoplastic tissues, controls the release of gastrointestinal hormones, the contraction of smooth muscle cells, and the proliferation of epithelial cells, among other aspects of the gastrointestinal and central nervous systems. The gastrin-releasing peptide receptor is the mechanism by which GRP has its effects. The phospholipase C signaling pathway is activated by this receptor, which is a 7-transmembrane G-protein coupled receptor that has been glycosylated. Numerous malignancies, including those of the lung, colon, and prostate, exhibit the receptor's abnormal expression. Autism and agoraphobia are two conditions connected to GRPR. Class A/1 (Rhodopsin-like receptors) and GPCR downstream signaling are two of its associated pathways. Bombesin receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.
| Full Name | Gastrin releasing peptide receptor |
| Gene ID | Human: 2925 Mouse: 14829 Rat: 24938 Monkey: 574339 |
| UniProt ID | Human: P30550 Mouse: P21729 Rat: P52500 Monkey: A0A2K5CFV6 |
| Alternative Names | BB2; BB2R; gastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor; bombesin receptor 2; GRPR; Gastrin releasing peptide receptor |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin Receptors Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRPR Target Family: Bombesin Family Target Protein Species: Human Host Cell Type: A549;CHO-K1;HEK293
