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    Family stable cell lines Metabotropic Glutamate Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human GRM8 Stable Cell Line

    [CAT#: S01YF-0923-PY126]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    GRM8
    Target Family
    Metabotropic Glutamate Family
    Target Protein Species
    Human
    Host Cell Type
    SK-BR-3;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Pain and Addiction Research;CNS Research
    Related Diseases
    Alcohol Dependence;Epilepsy
    Gene ID
    Human: 2918
    UniProt ID
    Human: O00222

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GRM8 is involved in encoding the metabotropic glutamate receptor 8 (mGluR8). This receptor has been associated with several physiological and pathological processes in the central nervous system. Research has shown that GRM8 plays a role in conditions such as ADHD, where it affects cognitive control. Additionally, GRM8 has been identified in the context of metastatic breast cancer, where its expression differs significantly in brain metastases compared to primary tumors.

    Protocols

    Please visit our protocols page.

    Customer Reviews

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    FAQ

    chat Sandra (Verified Customer)

    How is GRM8 associated with sperm quality in stallions? Oct 19 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Certain polymorphisms in the GRM8 gene are significantly associated with indicators of stallion sperm quality, including ejaculate volume, concentration, and progressive motility. Oct 19 2022

    chat Carol (Verified Customer)

    Can GRM8 variants be linked to eating disorders? Aug 30 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, rare single nucleotide variants in GRM8 have been identified as candidate factors associated with eating disorders in Japanese patients. Aug 30 2020

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    • mProX™ Human GRM8 Stable Cell Line (CAT#: S01YF-0923-PY126)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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