GRM8
The central nervous system's main excitatory neurotransmitter, L-glutamate, activates both ionotropic and metabotropic glutamate receptors. Most parts of normal brain function entail glutamatergic neurotransmission, which can be disturbed by a variety of neuropathologic disorders. GRM8-related illnesses include Creutzfeldt-Jakob disease. GPCR downstream signaling and sensory perception of taste are two of its linked pathways. G protein-coupled receptor activity and group III metabotropic glutamate receptor activity are two Gene Ontology (GO) annotations connected to this gene.
Full Name | Glutamate metabotropic receptor 8 |
Gene ID | Human: 2918 Mouse: 14823 Rat: 60590 Monkey: 102128797 |
UniProt ID | Human: O00222 Mouse: P47743 Rat: P70579 Monkey: Q4R7Q5 |
Alternative Names | GLUR8; mGlu8; GPRC1H; MGLUR8; glutamate receptor, metabotropic 8; GRM8; Glutamate metabotropic receptor 8 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Family Target Protein Species: Human Host Cell Type: SK-BR-3;CHO-K1;HEK293