GRM8
The central nervous system's main excitatory neurotransmitter, L-glutamate, activates both ionotropic and metabotropic glutamate receptors. Most parts of normal brain function entail glutamatergic neurotransmission, which can be disturbed by a variety of neuropathologic disorders. GRM8-related illnesses include Creutzfeldt-Jakob disease. GPCR downstream signaling and sensory perception of taste are two of its linked pathways. G protein-coupled receptor activity and group III metabotropic glutamate receptor activity are two Gene Ontology (GO) annotations connected to this gene.
| Full Name | Glutamate metabotropic receptor 8 |
| Gene ID | Human: 2918 Mouse: 14823 Rat: 60590 Monkey: 102128797 |
| UniProt ID | Human: O00222 Mouse: P47743 Rat: P70579 Monkey: Q4R7Q5 |
| Alternative Names | GLUR8; mGlu8; GPRC1H; MGLUR8; glutamate receptor, metabotropic 8; GRM8; Glutamate metabotropic receptor 8 |
Product List
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Magic™ Human FLAG tagged GRM8 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX455]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human FLAG tagged GRM8 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX453]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged GRM8 HEK293T Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX454]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
Magic™ Human GRM8 (NM_000845) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX753]
- Product Category:
- Membranes
- Target Protein: mGlu8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human GRM8 (NM_000845.1) HEK293T Gαqi5 Membrane Preparation
[CAT#: S01YF-0722-KX752]
- Product Category:
- Membranes
- Target Protein: mGlu8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human GRM8 (NM_000845.1) HEK293T Membrane Preparation
[CAT#: S01YF-0722-KX751]
- Product Category:
- Membranes
- Target Protein: mGlu8 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
mProX™ Human GRM8 Stable Cell Line
[CAT#: S01YF-0923-PY126]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM8 Target Family: Metabotropic Glutamate Family Target Protein Species: Human Host Cell Type: SK-BR-3;CHO-K1;HEK293 Assay Types: Biological assays
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