Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. GRM7
  3. mProX™ Human GRM7 Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP GPCR Cell Lines,Drug Discovery Tools
    Family stable cell lines Metabotropic Glutamate Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human GRM7 Stable Cell Line

    [CAT#: S01YF-0923-PY125]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Protein
    GRM7
    Target Family
    Metabotropic Glutamate Family
    Target Protein Species
    Human
    Host Cell Type
    H460;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Neurodevelopmental Disorder With Seizures, Hypotonia, And Brain Imaging Abnormalities;Autosomal Recessive Non-Syndromic Intellectual Disability.
    Gene ID
    Human: 2917
    UniProt ID
    Human: Q14831

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GRM7 is associated with the metabotropic glutamate receptor 7 (mGluR7). This receptor has been implicated in various neurological functions and disorders. Recent studies have identified mutations in GRM7 that are associated with neurodevelopmental disorders. Specifically, these mutations can lead to reduced expression of mGluR7, which in turn can cause neurological dysfunction. Additionally, GRM7 variants have been explored in the context of their association with psychiatric conditions such as schizophrenia.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GRM7 Stable Cell Line (S01YF-0923-PY125). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Dorothy (Verified Customer)

    How is GRM7 associated with neurological disorders? Oct 07 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Mutations in GRM7 have been linked to developmental delay and neurological dysfunction. Specific mutations can reduce mGlu7 expression, leading to neurological phenotypes. Oct 07 2021

    chat Amy (Verified Customer)

    What role does GRM7 play in axon and presynaptic terminal development? Jul 16 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Pathogenic GRM7 mutations can impair axon outgrowth and the development of presynaptic terminals. Stable neuronal surface expression of mGLU7 is essential for these neurological processes. Jul 16 2022

    Related Products by Target
    • mProX™ Human GRM7 Stable Cell Line (CAT#: S01YF-0923-PY125)
    • Magic™ Human FLAG tagged GRM7 HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX451)
    • Magic™ Human FLAG tagged GRM7 HEK293T Gαqi5 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX452)
    • Magic™ Human GRM7 CHO-K1 Cell Line, Binding and Functional Assay (CAT#: S01YF-1222-KX154)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare