GRM7
The central nervous system's main excitatory neurotransmitter, L-glutamate, activates both ionotropic and metabotropic glutamate receptors. Most parts of normal brain function entail glutamatergic neurotransmission, which can be disturbed by a variety of neuropathologic disorders. Microcephaly and Neurodevelopmental Disorder With Seizures, Hypotonia, And Brain Imaging Abnormalities are two conditions linked to GRM7. GPCR downstream signaling and sensory perception of taste are two of its linked pathways. This gene has PDZ domain binding and G protein-coupled receptor function as Gene Ontology (GO) annotations.
Full Name | Glutamate metabotropic receptor 7 |
Gene ID | Human: 2917 Mouse: 108073 Rat: 81672 Monkey: 702731 |
UniProt ID | Human: Q14831 Mouse: Q68ED2 Rat: P35400 Monkey: Q4R7Q5 |
Alternative Names | GLUR7; MGLU7; GPRC1G; MGLUR7; NEDSHBA; PPP1R87; glutamate receptor, metabotropic 7; protein phosphatase 1, regulatory subunit 87; GRM7; Glutamate metabotropic receptor 7 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM7 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM7 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM7 Target Family: Metabotropic Glutamate Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM7 Target Family: Metabotropic Glutamate Family Target Protein Species: Human Host Cell Type: H460;CHO-K1;HEK293