Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. GRIN1/GRIN2A
  3. mProX™ Human GRIN1/GRIN2A Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP Ion Channel Cell Lines,Drug Discovery Tools
    Family stable cell lines Glutamate Receptor Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human GRIN1/GRIN2A Stable Cell Line

    [CAT#: S01YF-1123-KX70]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Protein
    GRIN1/GRIN2A
    Target Family
    Glutamate Receptor
    Target Protein Species
    Human
    Host Cell Type
    COS-M6; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Neurodevelopmental Disorder
    Gene ID
    2902
    UniProt ID
    Q05586

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The human GRIN2A gene encodes the protein glutamate [NMDA] receptor subunit epsilon-1. The conventional GluN2A subunit isoform has a considerable length of 1464 amino acids. Alternative splicing can generate the monkey-specific GluN2A-short isoforms, which have 1281 amino acids. Ionotropic glutamate receptors include the N-methyl-D-aspartate (NMDA) receptor class. Long-term potentiation, an activity-dependent improvement in synaptic transmission efficiency believed to underpin some forms of memory and learning, has been linked to the NMDA channel. The main receptor subunit NMDAR1 (GRIN1) and one or more of the four NMDAR2 subunits-NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D)-compose heteromers that make up NMDA receptor channels. The customized GRIN1/GRIN2A stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GRIN1/GRIN2A Stable Cell Line (S01YF-1123-KX70). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Sharon (Verified Customer)

    What host cells are typically used for the GRIN1/GRIN2A stable cell line? Aug 17 2020

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Mammalian cells such as HEK293 or CHO-K1. Aug 17 2020

    chat Amy (Verified Customer)

    What is the BSL of the GRIN1/GRIN2A cell line? Dec 13 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    The BSL of the GRIN1/GRIN2A cell line is Level 1. Dec 13 2022

    Related Products by Target
    • Magic™ mPro Human GRIN1/GRIN2A Cell Line (CAT#: S01YF-1122-KX118)
    • mProX™ Human GRIN1/GRIN2A Stable Cell Line (CAT#: S01YF-1123-KX70)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare