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GRIN1/GRIN2A

Seven genetically encoded, differently expressed subunits, including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D), and NR3 make up the heterotetramers known as NMDA receptors (GRIN3A or GRIN3B). The early expression of this gene throughout development suggests a function in cellular migration and differentiation, synaptic plasticity, brain development, and circuit construction. Neurodevelopmental disorders such autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia are linked to naturally occurring mutations within this gene.

Full Name Glutamate ionotropic receptor NMDA type subunit 1
Gene ID Human: 2903
Mouse: 14811
Rat: 24409
Monkey: 100429880
UniProt ID Human: Q12879
Mouse: P35436
Rat: G3V9C5
Monkey: A0A1D5QE40
Alternative Names NR1; GluN1; NMDAR1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; NMDA R1 receptor C1 cassette; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; neurotransmitter receptor

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GRIN1/GRIN2A Target Family: Glutamate Receptor Target Protein Species: Human Host Cell Type: COS-M6; CHO-K1; HEK293
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GRIN1/GRIN2A Target Family: Ligand Gated Ion Channel; Glutamate Receptor Assay Target Protein Species: Rat Host Cell Type: HEK293 Assay Types: Electrophysiology Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GRIN1/GRIN2A Target Family: Ligand Gated Ion Channel; Glutamate Receptor Assay Target Protein Species: Human
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