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    mProX™ Human GPR34 Stable Cell Line

    [CAT#: S01YF-0923-PY164]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GPR34
    Target Family
    Orphan Family
    Target Protein Species
    Mouse
    Host Cell Type
    BV-2;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Ocular Research;CNS Research
    Related Diseases
    Alzheimer Disease 14;Night Blindness
    Gene ID
    Mouse: 23890
    UniProt ID
    Mouse: Q9R1K6

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GPR34 has been recognized for its role in mediating tissue repair. Specifically, it senses lysophosphatidylserine released by apoptotic neutrophils, activating type 3 innate lymphoid cells. Additionally, GPR34 has been implicated in salivary gland MALT lymphoma, where it potentially bridges lymphoepithelial lesions to the lymphoma's genesis. This receptor has also been associated with cognitive deficits in Alzheimer's disease, where its knockdown has been observed to relieve these deficits and suppress neuroinflammation.

    Protocols

    Please visit our protocols page.

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    There are currently no Customer reviews or questions for mProX™ Human GPR34 Stable Cell Line (S01YF-0923-PY164). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Amy (Verified Customer)

    In what way does GPR34 contribute to oncogenesis in cell lines? May 23 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR34 has been implicated in promoting glioma progression and regulating the proliferation of certain cancer cells. Its expression in stable cell line models enables the exploration of its oncogenic role and the underlying mechanisms in different cancer types​. May 23 2023

    chat Stephanie (Verified Customer)

    Are there any stable cell line models focusing on GPR34 knockdown? Dec 20 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, stable GPR34 knockdown cell models have been employed to study the effect of GPR34 on cell proliferation and tumor growth, providing valuable insights into its potential as a therapeutic target in cancer treatment. Dec 20 2020

    Related Products by Target
    • mProX™ Human GPR34 Stable Cell Line (CAT#: S01YF-0923-PY164)
    • Magic™ Human FLAG tagged GPR34 HEK293T Gαqi5 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX510)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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