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    mProX™ Human GPR132 Stable Cell Line

    [CAT#: S01YF-0923-PY199]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GPR132
    Target Family
    Orphan Family
    Target Protein Species
    Human
    Host Cell Type
    HL60;MV4-11;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Gene ID
    Human: 29933
    UniProt ID
    Human: Q9UNW8

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GPR132, also known as G2A, is a G-protein coupled receptor that has been implicated in various physiological and pathological processes. Recent studies have highlighted its role in immune cell function, particularly in macrophages and T cells. GPR132 has been shown to be involved in the regulation of inflammatory responses, and its activation can lead to the suppression of pro-inflammatory cytokine production. Furthermore, GPR132 has been linked to lipid metabolism, suggesting its potential role in atherosclerosis and other cardiovascular diseases. Given its diverse functions, GPR132 is emerging as a potential therapeutic target for inflammatory and metabolic disorders.

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    Please visit our protocols page.

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    FAQ

    chat Charles (Verified Customer)

    What role does GPR132 play in tumor progression? Jul 24 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPR132 can mediate interactions between tumors and macrophages. For instance, GPR132's sensing of lactate has been shown to promote breast cancer metastasis by influencing tumor-macrophage interplay. Jul 24 2020

    chat Laura (Verified Customer)

    How does GPR132 influence cell differentiation in leukemia? May 14 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Activation of GPR132 can induce cell differentiation in acute myeloid leukemia (AML). This suggests that GPR132 might be a potential therapeutic target for AML. May 14 2023

    Related Products by Target
    • mProX™ Human GPR132 Stable Cell Line (CAT#: S01YF-0923-PY199)
    • Magic™ Human GPR132 293F Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay (CAT#: S01YF-1222-KX143)
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