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    mProX™ Human GPC3 Stable Cell Line

    [CAT#: S01YF-1023-PY273]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;Huh-7
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Cancer Research
    Related Diseases
    Simpson-Golabi-Behmel Syndrome, Type 1; Wilms Tumor 1
    Gene ID
    Human:2719
    UniProt ID
    Human:P51654

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Glypican-3 (GPC3) is a heparan sulfate proteoglycan that has been extensively studied for its role in hepatocellular carcinoma (HCC). Its overexpression in HCC makes it a potential diagnostic and therapeutic target. Recent advancements have led to the development of GPC3-targeted immunoPET imaging strategies, offering superior diagnostic accuracies in preclinical HCC models. Furthermore, the modulation of the GPC3 pathway has shown promise in overcoming drug resistance in HCC, highlighting its significance in therapeutic interventions.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human GPC3 Stable Cell Line (S01YF-1023-PY273). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Morgan Johnson (Verified Customer)

    Is GPC3 a potential therapeutic target for small cell lung cancer (SCLC)? Oct 26 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPC3 has been identified as a potential therapeutic target for SCLC, with recombinant immunotoxins targeting GPC3 showing cytotoxicity to SCLC cells. Oct 26 2020

    chat Skyler Garcia (Verified Customer)

    Can GPC3 be used for imaging and therapy of hepatocellular carcinoma? Jun 16 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GPC3-targeted imaging and therapeutic strategies, such as immunoPET imaging and nanocarrier-based drug delivery, have shown promise in the detection and treatment of hepatocellular carcinoma expressing GPC3. Jun 16 2022

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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