Human GPC3 Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX400]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human GPC3 for Protein Expression.
Target Protein
GPC3
Target Protein Species
Human
Target Classification
Others
Target Research Area
Cancer Research
Related Diseases
Simpson-Golabi-Behmel Syndrome; Wilms Tumor
Target Family
Others
Vector
pME
Vector Type
Mammalian Transient Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
CMV, SV40, EF1a, CAG etc.
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Glypican 3
Introduction
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Alternative Names
SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; glypican-3; glypican proteoglycan 3; heparan sulphate proteoglycan; intestinal protein OCI-5; secreted glypican-3
Gene ID
UniProt ID
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