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  • Human GPC3 Membrane Protein In Vitro Transcription (IVT) mRNA

    [CAT#: S01YF-1124-KX170]
    Product Category:
    Membrane Protein Tools
    Subcategory:
    Membrane Protein mRNA

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    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Product Information

    Product Overview
    This product is a made-to-order IVT mRNA encoding human GPC3.
    Target Protein
    GPC3
    Target Protein Species
    Human
    Target Classificationp
    Others
    Target Research Area
    Cancer Research
    Related Diseases
    Simpson-Golabi-Behmel Syndrome; Wilms Tumor
    Target Family
    Others
    RNA Type
    IVT mRNA
    Nucleoside Modification Method
    m1Ψ; m5C or specific requirements
    Cap
    Cap 0; Cap 1 or specific requirements
    PolyA Tail (nt)
    30 nt; 80 nt; 120 nt or specific requirements
    5' UTR
    Human globin alpha; 5' UTR seq can be modified according to the specific requirements
    Promoter
    T7
    Tag
    Based on specific requirements
    Fluorescent Markers
    Based on specific requirements
    Formation
    In Vitro Transcription (IVT) mRNA

    Quality Control

    OD260/280 (~1.90-2.50)
    PASS
    Agarose Gel Mobility
    PASS
    Sequence and Enzyme Digestion
    PASS

    Product Properties

    Application
    Drug discovery research and pre-clinical studies
    Shipping
    Dry Ice
    Storage
    Aliquot and store at -20°C for long term.

    Target

    Full Name
    Glypican 3
    Introduction
    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
    Alternative Names
    SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; glypican-3; glypican proteoglycan 3; heparan sulphate proteoglycan; intestinal protein OCI-5; secreted glypican-3
    Gene ID
    UniProt ID

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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