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    mProX™ Human GNRHR Stable Cell Line

    [CAT#: S01YF-0923-PY86]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GNRHR
    Target Family
    Gonadotrophin-releasing Hormone Family
    Target Protein Species
    Monkey
    Host Cell Type
    COS-7;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Hypogonadotropic Hypogonadism 7 With Or Without Anosmia;Infertility
    Gene ID
    Monkey: 711577

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Gonadotropin-releasing hormone receptor (GNRHR) is pivotal in the regulation of the reproductive system. Polymorphisms in the GNRHR gene have been associated with fertility traits in livestock, suggesting its potential in marker-assisted selection. Furthermore, GNRHR has been linked to conditions like congenital idiopathic hypogonadotropic hypogonadism, emphasizing its role in reproductive health. Additionally, the association between GNRHR gene variants and conditions like polycystic ovary syndrome has been explored, highlighting its significance in reproductive disorders.

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    Customer Reviews

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    FAQ

    chat Paul (Verified Customer)

    What is the significance of the GnRHR expression in the human spinal cord? Feb 22 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The presence of gonadotropin-releasing hormone receptor (GnRHR) in the spinal cord suggests a potential extrapituitary functional role that is independent of the reproductive system. Feb 22 2020

    chat Paul (Verified Customer)

    How do GNRHR gene variants impact congenital idiopathic hypogonadotropic hypogonadism (CHH)? Jul 26 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Biallelic variants in the GNRHR gene can lead to a severe reproductive phenotype characterized by low gonadotropin levels without nonreproductive features or oligogenicity. However, the role of monoallelic GNRHR variants in CHH remains uncertain for some reported variants. Jul 26 2021

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