GNRHR
The receptor for type 1 gonadotropin-releasing hormone is encoded by this gene. The seven-transmembrane G-protein coupled receptor (GPCR) family includes this receptor. Pituitary gonadotrope cells, lymphocytes, breast, ovary, and prostate all express it on their outer surfaces. A phosphatidylinositol-calcium second messenger system is activated by the receptor's association with G proteins after gonadotropin-releasing hormone binding. The release of follicle stimulating hormone (FSH) and gonadotropic luteinizing hormone results from activation of the receptor. Hypogonadotropic hypogonadism is brought on by errors in this gene.
Full Name | Gonadotropin releasing hormone receptor |
Gene ID | Human: 2798 Mouse: 14715 Rat: 81668 Monkey: 105731588 |
UniProt ID | Human: P30968 Mouse: Q01776 Rat: P30969 Monkey: A0A2K5C7S7 |
Alternative Names | HH7; GRHR; LRHR; LHRHR; GNRHR1; gonadotropin-releasing hormone receptor; gnRH receptor; gnRH-R; gonadotropin-releasing hormone (type 1) receptor 1; leutinizing hormone releasing horomone receptor; leutinizing-releasing hormone receptor; luliberin receptor; type I GnRH receptor; GNRHR; Gonadotropin releasing hormone receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GNRHR Target Family: Gonadotrophin-Releasing Hormone Target Protein Species: Dog Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GNRHR Target Family: Gonadotrophin-Releasing Hormone Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GNRHR Target Family: Gonadotropin releasing hormone receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GnRHR Target Family: Gonadotropin releasing hormone receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GNRHR Target Family: Gonadotropin releasing hormone receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GNRHR Target Family: Gonadotrophin-releasing Hormone Family Target Protein Species: Monkey Host Cell Type: COS-7;CHO-K1;HEK293