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    mProX™ Human GNRH1 Stable Cell Line

    [CAT#: S01YF-0923-PY85]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GNRH1
    Target Family
    Gonadotrophin-releasing Hormone Family
    Target Protein Species
    Human
    Host Cell Type
    hPSCs;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Hypogonadotropic Hypogonadism 12 With Or Without Anosmia;Normosmic Congenital Hypogonadotropic Hypogonadism
    Gene ID
    Human: 2796
    UniProt ID
    Human: P01148

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Gonadotropin-releasing hormone 1 (GNRH1) plays a crucial role in the regulation of the reproductive system. Recent studies have highlighted the role of GNRH1 in conditions like congenital hypogonadotropic hypogonadism, emphasizing its significance in reproductive health. Additionally, the association between GNRH1 and various reproductive disorders, such as polycystic ovarian syndrome, has been explored, suggesting its potential as a diagnostic and therapeutic target.

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    Please visit our protocols page.

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    FAQ

    chat Sandra (Verified Customer)

    Are there any associations between GNRH1 variants and congenital hypogonadotropic hypogonadism (CHH)? Jun 28 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Biallelic variants in the GNRH1 gene lead to a severe reproductive phenotype characterized by low gonadotropin levels without nonreproductive features or oligogenicity. However, the role of monoallelic GNRH1 variants in CHH remains uncertain for some reported variants. Jun 28 2022

    chat Richard (Verified Customer)

    How might GNRH1 and LTB4R be relevant in clear cell renal cell carcinoma (ccRCC)? Apr 04 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GNRH1 and LTB4R have been identified as potential immune-related prognostic biomarkers in ccRCC. These markers show a strong correlation with the prognosis of patients with ccRCC and could be used as potential prognostic indicators. Apr 04 2023

    Related Products by Target
    • mProX™ Human GNRH1 Stable Cell Line (CAT#: S01YF-0923-PY85)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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