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    mProX™ Human GLP2R Stable Cell Line

    [CAT#: S01YF-0923-PY79]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GLP2R
    Target Family
    Glucagon Family
    Target Protein Species
    Human
    Host Cell Type
    PC9;HCC827;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Digestive and Renal Research
    Related Diseases
    Bowel Dysfunction;Short Bowel Syndrome
    Gene ID
    Human: 9340
    UniProt ID
    Human: O95838

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The glucagon-like peptide 2 receptor (GLP2R) has been the subject of various scientific studies, revealing its potential implications in diverse medical conditions. For instance, the GLP-2-GLP2R signaling pathway has been identified as a potential modulator of sensitivity to EGFR-TKIs, a class of drugs used in lung cancer treatment. Additionally, GLP-2R plays a pivotal role in hepatic adaptation to nutrient excess, suggesting its significance in liver-related disorders. Furthermore, GLP2R's involvement in the methylation status among Small for Gestational Age (SGA) patients has been explored, indicating its potential role in growth and development. Collectively, these findings underscore the importance of GLP2R in various physiological processes and its potential as a therapeutic target in multiple diseases.

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    FAQ

    chat Helen (Verified Customer)

    What is the role of GLP2-GLP2R signaling in lung cancer treatment? Feb 23 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The GLP-2-GLP2R signaling may alter the sensitivity of cells to EGFR-TKIs and cisplatin, suggesting its potential benefit in the clinical treatment of lung cancer. Feb 23 2023

    chat Timothy (Verified Customer)

    How does the loss of Glp2r signaling affect hepatic stellate cells? Feb 10 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The loss of GLP-2R signaling activates hepatic stellate cells and exacerbates diet-induced steatohepatitis in mice, indicating its essential role in hepatic adaptation to nutrient excess. Feb 10 2023

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