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    mProX™ Human GALR2 Stable Cell Line

    [CAT#: S01YF-0923-PY72]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    GALR2
    Target Family
    Galanin Family
    Target Protein Species
    Rat
    Host Cell Type
    H9C2;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Epilepsy;Alzheimer Disease
    Gene ID
    Rat: 29234
    UniProt ID
    Rat: O08726

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Galanin Receptor 2 (GALR2) is a G-protein coupled receptor that binds the neuropeptide galanin. This receptor plays a significant role in various physiological processes, including the modulation of mood and behavior. Recent studies have highlighted the potential of GALR2 as a therapeutic target for mood disorders. For instance, the activation of GALR2 has been linked to anti-depressant-like effects in animal models. Additionally, GALR2 has been implicated in the regulation of feeding behavior, suggesting its potential role in obesity and metabolic disorders. The diverse roles of GALR2 in the central nervous system make it a promising target for drug development in neuropsychiatric and metabolic disorders.

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    FAQ

    chat Laura (Verified Customer)

    How does the GAL/GALR2 axis influence the perineural invasion of salivary adenoid cystic carcinoma? Jun 22 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The nerve-derived neuropeptide galanin (GAL) and its receptor (GALR2) play a role in the regulation of perineural invasion (PNI) in salivary adenoid cystic carcinoma, suggesting a potential mechanism for tumor progression. Jun 22 2020

    chat Kathleen (Verified Customer)

    Can the GALR2 receptor be involved in the protective action against myocardial injury during reperfusion? Oct 22 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, studies suggest that the GalR2 receptor participates in the protective action of certain chimeric agonists on the heart subjected to ischemia and reperfusion, indicating its potential therapeutic value in cardiovascular diseases. Oct 22 2021

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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