Recommended
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
  • mProX™ Human GABRA1 Stable Cell Line

    [CAT#: S01YF-1123-KX64]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Protein
    GABRA1
    Target Family
    GABAA
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Epilepsy; Developmental And Epileptic Encephalopathy
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The GABRA1 gene codes for the alpha-1 (α1) subunit, which is a single component of the GABAA receptor protein. Gamma-amino butyric acid (GABA) is a neurotransmitter that binds to GABAA receptors in the brain to transfer messages. The opening created by the subunits opens when GABA connects, allowing chloride ions to pass through the cell membrane. Chloride ions enter the cell through the open pore after infancy, creating an environment that prevents or inhibits neuronal activation. In both toddlers and adults, the main function of GABA is to keep the brain from becoming overstimulated by too many messages. On the other hand, when the pore is opened in neonates and babies, chloride ions flow out of the cell, facilitating signaling between neurons. The customized GABRA1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Helen

    The cell line was exactly what I was looking for. Apr 08 2023

    chat Verified Customer

    chat Timothy

    I was so pleased with the service I received from this business. Apr 17 2023

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare