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GABRA1

Gamma-aminobutyric acid (GABA) receptor is encoded by this gene. The GABA-A receptors, which are ligand-gated chloride channels, are where GABA works as the main inhibitory neurotransmitter in the mammalian brain. These channels' chloride conductance can be altered by substances like benzodiazepines that attach to the GABA-A receptor. GABA-A receptors are pentameric and made up of proteins from the alpha, beta, gamma, delta, and rho subunit classes. Juvenile myoclonic epilepsy and type 4 absence epilepsy in children are both caused by mutations in this gene.

Full Name Gamma-aminobutyric acid type A receptor subunit alpha1
Gene ID Human: 2554
Mouse: 14394
Rat: 29705
Monkey: 574302
UniProt ID Human: P14867
Mouse: P62812
Rat: P62813
Monkey: F7F7H3
Alternative Names EJM; ECA4; EJM5; DEE19; EIEE19; GABA(A) receptor subunit alpha-1; GABA(A) receptor, alpha 1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid type A receptor alpha1 subunit; GABRA1; Gamma-aminobutyric acid type A receptor subunit alpha1

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GABAA1/α1β2γ2 Target Family: Ligand Gated Ion Channel; GABAA Assay Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GABAA1/α1β3γ2 Target Family: Ligand Gated Ion Channel; GABAA Assay Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GABRA1 Target Family: GABAA Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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