GABRA1
Gamma-aminobutyric acid (GABA) receptor is encoded by this gene. The GABA-A receptors, which are ligand-gated chloride channels, are where GABA works as the main inhibitory neurotransmitter in the mammalian brain. These channels' chloride conductance can be altered by substances like benzodiazepines that attach to the GABA-A receptor. GABA-A receptors are pentameric and made up of proteins from the alpha, beta, gamma, delta, and rho subunit classes. Juvenile myoclonic epilepsy and type 4 absence epilepsy in children are both caused by mutations in this gene.
Full Name | Gamma-aminobutyric acid type A receptor subunit alpha1 |
Gene ID | Human: 2554 Mouse: 14394 Rat: 29705 Monkey: 574302 |
UniProt ID | Human: P14867 Mouse: P62812 Rat: P62813 Monkey: F7F7H3 |
Alternative Names | EJM; ECA4; EJM5; DEE19; EIEE19; GABA(A) receptor subunit alpha-1; GABA(A) receptor, alpha 1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid type A receptor alpha1 subunit; GABRA1; Gamma-aminobutyric acid type A receptor subunit alpha1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GABAA1/α1β2γ2 Target Family: Ligand Gated Ion Channel; GABAA Assay Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GABAA1/α1β3γ2 Target Family: Ligand Gated Ion Channel; GABAA Assay Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GABRA1 Target Family: GABAA Target Protein Species: Human Host Cell Type: CHO-K1; HEK293