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    mProX™ Human FSHR Stable Cell Line

    [CAT#: S01YF-0923-PY82]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    FSHR
    Target Family
    Glycoprotein Hormone Family
    Target Protein Species
    Human
    Host Cell Type
    HUVECs;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Ovarian Dysgenesis 1;Ovarian Hyperstmulation Syndrome
    Gene ID
    Human: 2492
    UniProt ID
    Human: P23945

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Follicle-stimulating hormone receptor (FSHR) plays a crucial role in reproductive physiology. Polymorphisms in the FSHR gene have been associated with ovarian response, suggesting its significance in fertility treatments. Additionally, FSHR has been identified as a potential target for immunotherapy in ovarian cancer. Moreover, FSHR's involvement in polycystic ovary syndrome (PCOS) has been explored, indicating its role in this common endocrine disorder. Collectively, these findings underscore the importance of FSHR in reproductive health and its potential as a therapeutic target in various reproductive disorders.

    Protocols

    Please visit our protocols page.

    Customer Reviews

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    FAQ

    chat Richard (Verified Customer)

    What insights does the study provide about FSH-FSHR biology in relation to stem cells? Mar 30 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FSH has a direct action on stem cells in addition to their well-known action on Granulosa and Sertoli cells in the ovaries and testes. This explains why multiple solid as well as liquid tumors express OCT-4 and FSHR. Mar 30 2022

    chat Robert (Verified Customer)

    How do polymorphisms in FSHR modulate susceptibility to polycystic ovary syndrome (PCOS)? Jun 26 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    A meta-analysis suggests that the GG genotype of rs6166 provides protection against PCOS in a population-specific manner. Jun 26 2021

    Related Products by Target
    • mProX™ Human FSHR Stable Cell Line (CAT#: S01YF-0923-PY82)
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