Recommended
Membrane Protein Drug Discovery In Vitro Assays Membrane Protein In Vitro Assay Kits Membrane Protein Stable Cell Lines Membranes Membrane Protein Virus Particles Membrane Staining and Imaging Reagents
  1. Home
  2. FFAR3
  3. mProX™ Human FFAR3 Stable Cell Line
product-img
  • Products
  • Discover MP Targets
  • Discover Research Areas
    • 1- Membrane Protein Stable Cell Line-DiscoverMP Membrane Protein Stable Cell Line, Drug Discovery Tools
    1- Membrane Protein Stable Cell Line-DiscoverMP GPCR Cell Lines,Drug Discovery Tools
    Family stable cell lines Free Fatty Acid Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human FFAR3 Stable Cell Line

    [CAT#: S01YF-0923-PY68]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Bulk Quote

    Made to Order Inquiry

    Inquiry
    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Protein
    FFAR3
    Target Family
    Free Fatty Acid Family
    Target Protein Species
    Human
    Host Cell Type
    NCM460;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Digestive and Renal Research
    Related Diseases
    Diversion Colitis;Anaerobic Meningitis
    Gene ID
    Human: 2865

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    FFAR3, also known as GPR41, is intricately linked with various metabolic and immune processes. One of its notable roles is in the heart, where it has been associated with dampening of FFAR3 signaling in cardiomyocytes, influencing cAMP levels and pro-inflammatory interleukin production. Additionally, the gut-lung axis has been highlighted, where gut-derived short-chain fatty acids (SCFAs) can influence lung immune tone, with FFAR3 playing a pivotal role in this interaction. Furthermore, FFAR3's expression in vagal neurons has been linked to the regulation of feeding behavior, suggesting its potential role in appetite control.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human FFAR3 Stable Cell Line (S01YF-0923-PY68). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Anthony (Verified Customer)

    How does FFAR3 contribute to the regulation of pancreatic endocrine secretion in mice? Aug 11 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The effects of certain compounds on somatostatin secretion suggest that it may be possible to manipulate pancreatic secretion pharmacologically with agonists of the FFAR2 and 3 receptors. Aug 11 2021

    chat Paul (Verified Customer)

    What is the significance of FFAR3 in cardiac regulation? Nov 13 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Pressure overload upregulates cardiac RGS4 to protect the heart against FFAR3-mediated inflammation and elevated sympathetic nervous system activity. Nov 13 2021

    Related Products by Target
    • Magic™ Human FLAG tagged FFAR3 CHO-K1 Gα16 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX329)
    • Magic™ Rat FLAG tagged FFAR3 HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX332)
    • Magic™ Human FLAG tagged FFAR3 HEK293T Gαqi5 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX330)
    • Magic™ mPro Human FFAR3 Cell Line (CAT#: S01YF-1122-KX29)
    • Magic™ Mouse FLAG tagged FFAR3 CHO-K1 Gα16 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX331)
    • Magic™ Human FLAG tagged FFAR3 HEK293T Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX328)
    • mProX™ Human FFAR3 Stable Cell Line (CAT#: S01YF-0923-PY68)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
    Send Inquiry Send Inquiry
    Inquiry Basket
    compare

    Go to compare