F2RL3
A protein from the G-protein coupled receptor 1 family is encoded by this gene. The extracellular amino terminus of the encoded cell surface receptor is cleaved by proteases, which produces a new amino terminus that functions as a tethered ligand that binds to an extracellular loop domain. It has been demonstrated that activating the receptor causes blood vessels to widen, improves blood flow, and lowers blood pressure. Along with innate and adaptive immunity, this protein is crucial for the inflammatory response.
| Full Name | F2R like thrombin or trypsin receptor 3 |
| Gene ID | Human: 9002 Mouse: 14065 Rat: 116498 Monkey: 718843 |
| UniProt ID | Human: Q96RI0 Mouse: O88634 Rat: Q920E0 Monkey: A0A2K5ELK3 |
| Alternative Names | F2RL3; PAR4; proteinase-activated receptor 4; F2R like thrombin/trypsin receptor 3; PAR-4; coagulation factor II (thrombin) receptor-like 3; protease-activated receptor-4; thrombin receptor-like 3; F2R like thrombin or trypsin receptor 3 |
Product List
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Magic™ Human F2RL3 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX146]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human F2RL3 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX100]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-activated receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human FLAG tagged F2RL3 HeLa Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX559]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Assay Types: Calcium flux assay
Magic™ mPro Human F2RL3 Cell Line
[CAT#: S01YF-1122-KX52]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-Activated Target Protein Species: Human
mProX™ Human F2RL3 Stable Cell Line
[CAT#: S01YF-0923-KX16]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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