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    mProX™ Human DRD5 Stable Cell Line

    [CAT#: S01YF-0923-PY63]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX416 Magic™ Rat DRD5 in Vitro cAMP Assay Rat CHO-K1 cAMP Assay

    Product Information

    Target Protein
    DRD5
    Target Family
    Dopamine Family
    Target Protein Species
    Human
    Host Cell Type
    HeLa;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Blepharospasm, Benign Essential;Attention Deficit-Hyperactivity Disorder
    Gene ID
    Human: 1816
    UniProt ID
    Human: P21918

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The Dopamine Receptor D5 (DRD5) is another critical component of the dopamine system. It has been associated with various physiological and pathological processes. For instance, research has shown that DA-DRD5 signaling can control colitis by regulating M1/M2 macrophage polarization. Another study highlighted the potential of DRD5 in suppressing systemic inflammation through a specific signaling axis. Furthermore, the hypermethylation of the DRD5 promoter has been identified as a potential biomarker across different cancer types. The diverse roles of DRD5 in health and disease underscore its importance in scientific research and its potential therapeutic applications.

    Protocols

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human DRD5 Stable Cell Line (S01YF-0923-PY63). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Sarah (Verified Customer)

    What role does DRD5 play in scientific research? Dec 26 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    DRD5, or dopamine receptor D5, is another critical receptor in the dopamine system. It has been associated with various physiological and pathological processes. For instance, a relationship has been observed between the DRD5 VNTR polymorphism and paranoid personality disorder, suggesting a monoaminergic basis for certain personality disorders. Additionally, DRD5 has been implicated in the regulation of macrophage polarization, influencing inflammatory responses and potentially playing a role in conditions like colitis. Dec 26 2022

    chat Deborah (Verified Customer)

    How does DRD5 impact cancer research? Mar 05 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Recent studies have highlighted the role of DRD5 in tumor growth and the Warburg effect in esophageal cancer. The dopamine pathway mediated by DRD5 has been shown to influence the tumor immune microenvironment, offering potential therapeutic targets for metastatic cancers. Understanding the role of DRD5 in cancer can pave the way for novel therapeutic strategies and better patient outcomes. Mar 05 2022

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    • mProX™ Human DRD5 Stable Cell Line (CAT#: S01YF-0923-PY63)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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