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    mProX™ Human DRD2 Stable Cell Line

    [CAT#: S01YF-0923-PY60]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX406 Magic™ Mouse DRD2S in Vitro cAMP Assay Mouse CHO-K1 cAMP Assay
    S01YF-1122-KX407 Magic™ Rat DRD2S in Vitro cAMP Assay Rat CHO-K1 cAMP Assay

    Product Information

    Target Protein
    DRD2
    Target Family
    Dopamine Family
    Target Protein Species
    Human
    Host Cell Type
    HCT116;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Pain and Addiction Research;CNS Research
    Related Diseases
    Cocaine Dependence;Substance Dependence
    Gene ID
    Human: 1813
    UniProt ID
    Human: P14416

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    DRD2, the Dopamine receptor D2, is another subtype of dopamine receptors. It has been extensively studied for its role in various neurological and psychiatric disorders. Polymorphisms in the DRD2 gene have been associated with individual responses to psychiatric treatments, suggesting its importance in precision medicine. Moreover, DRD2 has been implicated in the progression of malignant tumors, especially under psychological stress conditions. The potential of DRD2 antagonists in enhancing the efficacy of chemoradiotherapy in certain cancers has also been explored. The multifaceted roles of DRD2 in the brain and its involvement in various diseases make it a focal point of scientific research.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human DRD2 Stable Cell Line (S01YF-0923-PY60). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Lisa (Verified Customer)

    What is the role of DRD2 in scientific investigations? Jul 10 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    DRD2, or Dopamine receptor D2, is another receptor for dopamine and plays a complementary role to DRD1 in the brain's dopaminergic pathways. It is heavily implicated in reward and pleasure circuits, and its dysregulation is associated with conditions like addiction, schizophrenia, and certain types of tumors. Jul 10 2023

    chat Jason (Verified Customer)

    How does DRD2 influence therapeutic responses in certain conditions? Jan 27 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    DRD2 has been identified as a target for various therapeutic interventions, especially in psychiatric disorders. For instance, many antipsychotic drugs act by modulating DRD2 activity. Additionally, recent research has shown that DRD2 can influence the sensitivity of certain tumors to treatments, suggesting its potential role in cancer therapy. Jan 27 2023

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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