DRD2
The D2 subtype of the dopamine receptor is encoded by this gene. The activity of adenylyl cyclase is inhibited by this G-protein coupled receptor. Myoclonus dystonia is brought on by a missense mutation in this gene; other variants have been linked to schizophrenia. Adenylyl cyclase is inhibited by G proteins, which are involved in the functioning of the dopamine receptor. suppresses VEGFR2/KDR activity, which is downstream of OPN5, to control postnatal regression of retinal hyaloid vessels.
| Full Name | Dopamine receptor D2 |
| Gene ID | Human: 1813 Mouse: 13489 Rat: 24318 Monkey: 694181 |
| UniProt ID | Human: P14416 Mouse: P61168 Rat: P61169 Monkey: P52702 |
| Alternative Names | D2R; D2DR; D(2) dopamine receptor; dopamine D2 receptor; seven transmembrane helix receptor; DRD2; Dopamine receptor D2 |
Product List
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Magic™ Human DRD2 Cell Line with 14-3-3γ Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX129]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human DRD2 Cell Line with 14-3-3ε Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX128]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human DRD2 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX336]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human DRD2 CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX49]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Magic™ Human DRD2 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX47]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human DRD2 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX67]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged DRD2 & GHSR HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX300]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2; GHSR Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged DRD2 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX299]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
mProX™ Human DRD2 Stable Cell Line
[CAT#: S01YF-0923-PY60]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Family Target Protein Species: Human Host Cell Type: HCT116;CHO-K1;HEK293
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