DRD2
The D2 subtype of the dopamine receptor is encoded by this gene. The activity of adenylyl cyclase is inhibited by this G-protein coupled receptor. Myoclonus dystonia is brought on by a missense mutation in this gene; other variants have been linked to schizophrenia. Adenylyl cyclase is inhibited by G proteins, which are involved in the functioning of the dopamine receptor. suppresses VEGFR2/KDR activity, which is downstream of OPN5, to control postnatal regression of retinal hyaloid vessels.
Full Name | Dopamine receptor D2 |
Gene ID | Human: 1813 Mouse: 13489 Rat: 24318 Monkey: 694181 |
UniProt ID | Human: P14416 Mouse: P61168 Rat: P61169 Monkey: P52702 |
Alternative Names | D2R; D2DR; D(2) dopamine receptor; dopamine D2 receptor; seven transmembrane helix receptor; DRD2; Dopamine receptor D2 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2; GHSR Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: DRD2 Target Family: Dopamine Family Target Protein Species: Human Host Cell Type: HCT116;CHO-K1;HEK293