mProX™ Human CSF1R Stable Cell Line
[CAT#: S01YF-1123-KX245]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
CSF1R
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
SKBR3; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
CNS Research; Reproductive Research
Related Diseases
Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1 and Brain Abnormalities, Neurodegeneration, And Dysosteosclerosis. Among its related pathways are GPCR Pathway and ERK Signaling
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The human CSF1R gene encodes the cell-surface protein known as colony stimulating factor 1 receptor (CSF1R), sometimes referred to as CD115 and macrophage colony-stimulating factor receptor (M-CSFR). Two ligands, colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34), can activate the CSF1R receptor. Myeloid cells have high expression levels of CSF1R, and both in vivo and in vitro myeloid cell types cannot survive, proliferate, or differentiate without CSF1R signaling. Treatments for cancer, neurodegeneration, and inflammatory bone diseases all target CSF1R signaling, which is implicated in a variety of diseases. The customized CSF1R stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Barbara
The CSF1R cell line is easy to use and has become an essential tool in my lab.
Mar 20 2020
Verified Customer
Michael
The CSF1R cell line allowed me to perform rigorous experiments with consistent results.
Oct 31 2021
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
