Human CSF1R Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX841]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
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Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human CSF1R for Lentivirus Production.
Target Protein
CSF1R
Target Protein Species
Human
Target Classification
Kinases/Enzyme
Target Research Area
CNS Research
Related Diseases
Leukoencephalopathy, Hereditary Diffuse, With Spheroids; Brain Abnormalities, Neurodegeneration, And Dysosteosclerosis
Target Family
Kinases/Enzyme
Vector
pLV
Vector Type
Lentiviral Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
CMV, SV40, EF1a, CAG etc.
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Product Properties
Applications
Lentivirus Production
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Colony stimulating factor 1 receptor
Introduction
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Alternative Names
CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; BANDDOS; M-CSF-R; macrophage colony-stimulating factor 1 receptor; CD115 antigen; CSF-1 receptor; FMS proto-oncogene; McDonough feline sarcoma viral (v-fms) oncogene homolog; macrophage colony stimulating factor I receptor; proto-oncogene c-Fms; Colony stimulating factor 1 receptor
Gene ID
UniProt ID
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