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    mProX™ Human CRHR2 Stable Cell Line

    [CAT#: S01YF-0923-PY58]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX394 Magic™ Rat CRF2a in Vitro cAMP Assay Rat CHO-K1 cAMP Assay

    Product Information

    Target Protein
    CRHR2
    Target Family
    CRF Receptor Family
    Target Protein Species
    Human
    Host Cell Type
    NCM460;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Digestive and Renal Research
    Related Diseases
    Irritable Bowel Syndrome;Eating Disorder
    Gene ID
    Human: 1395
    UniProt ID
    Human: Q13324

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CRHR2, the Corticotropin-releasing hormone receptor 2, is another receptor involved in the stress response system. Unlike CRHR1, CRHR2 has been associated with anti-stress effects. Research has shown that activation of CRHR2 can lead to reduced anxiety-like behaviors. This receptor is predominantly found in the cardiovascular system, and its activation has cardioprotective effects, especially during conditions of ischemic heart disease. The potential of CRHR2 agonists in treating heart diseases and stress-related disorders makes it a significant focus of scientific research.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CRHR2 Stable Cell Line (S01YF-0923-PY58). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Matthew (Verified Customer)

    What role does CRHR2 play in scientific research? Oct 15 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CRHR2, or Corticotropin-releasing hormone receptor 2, is another receptor involved in the body's stress response system. Scientific studies have shown that CRHR2 has distinct functions from CRHR1, particularly in the areas of cardiovascular regulation, inflammation, and feeding behavior. Its involvement in these processes makes it a subject of interest in research related to cardiovascular diseases, inflammatory conditions, and metabolic disorders. Oct 15 2021

    chat Cynthia (Verified Customer)

    How is CRHR2 associated with inflammation and feeding behavior? Dec 17 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CRHR2 has been found to modulate inflammatory responses in various tissues, suggesting its potential role in inflammatory diseases. Additionally, its expression in certain regions of the brain indicates its involvement in regulating feeding behavior, which can have implications for conditions like obesity and eating disorders. Dec 17 2022

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    • mProX™ Human CRHR2 Stable Cell Line (CAT#: S01YF-0923-PY58)
    • Magic™ Human CRHR2 CHO-K1/Gα15 Cell Line, Calcium flux assay (CAT#: S01YF-1022-KX46)
    • Magic™ Human CRHR2 CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay (CAT#: S01YF-1222-KX47)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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