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    mProX™ Human CNR1 Stable Cell Line

    [CAT#: S01YF-0923-PY29]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX261 Magic™ Rhesus monkey CNR1 in Vitro cAMP Assay Rhesus monkey CHO-K1 cAMP Assay
    S01YF-1122-KX262 Magic™ Rabbit CNR1 in Vitro cAMP Assay Rabbit CHO-K1 cAMP Assay

    Product Information

    Target Protein
    CNR1
    Target Family
    Cannabinoid Family
    Target Protein Species
    Human
    Host Cell Type
    Ishikawa;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Cannabis Dependence;Cannabis Abuse
    Gene ID
    Human: 1268
    UniProt ID
    Human: P21554

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The CNR1 gene, which encodes the cannabinoid receptor-1 (CB1), has been extensively studied in the context of neuroscience, pharmacology, and genetics. One of the groundbreaking studies developed and validated CRISPR activator systems for overexpressing CB1 receptors in neurons, demonstrating the efficiency in increasing mRNA and protein expression of the Cnr1 gene. Additionally, the CNR1 gene has been associated with various behavioral and psychological conditions. For instance, the rs1049353 polymorphism in the CNR1 gene has been shown to interact with childhood abuse to predict posttraumatic threat symptoms. Moreover, the CNR1 gene has been implicated in the risk of synthetic cannabinoid use disorder, although some studies suggest that certain CNR1 gene polymorphisms do not influence this risk. These studies highlight the multifaceted role of CNR1 in human health and disease, emphasizing its importance in scientific research.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CNR1 Stable Cell Line (S01YF-0923-PY29). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Jason (Verified Customer)

    Are there any known challenges associated with CNR1 in cell line stabilization? Oct 27 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    While specific challenges related to CNR1 are not explicitly mentioned, cell line stabilization often requires addressing issues like genomic integrity and DNA damage repair. Oct 27 2021

    chat Robert (Verified Customer)

    How does CNR1 expression impact cell behavior in research settings? Jul 14 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CNR1 expression can influence various cellular behaviors, including proliferation, migration, and response to external stimuli. Understanding its role can aid in drug development and therapeutic strategies. Jul 14 2023

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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