mProX™ Human CLCN1 Stable Cell Line
[CAT#: S01YF-1123-KX89]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Ion Channel Cell Lines
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The CLCN1 gene codes for the production of a particular class of protein known as a chloride channel. The instructions needed to create the ClC-1 chloride channel are encoded by the CLCN1 gene. Only skeletal muscles-the muscles employed for movement-have these channels. The passage of chloride ions into these cells is regulated by ClC-1 channels, which are found across the cell membrane. The electrical charge of the cells is stabilized by this inflow, preventing aberrant muscular contraction. Two identical protein subunits, both derived from the CLCN1 gene, make up ClC-1 channels. The two proteins cooperate to control the amount of chloride ions that enter skeletal muscle cells, even though each subunit creates a distinct hole (pore) for the ions to travel through. The customized CLCN1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Linda
This CLCN1 cell line is the best choice for laboratories wishing to minimise troubleshooting time and maximise data and experimental volumes.
Oct 31 2022
Verified Customer
Shirley
The ideal CLCN1 cell line, often used in our laboratories.
Jun 28 2020
Verified Customer
FAQ
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