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    Family stable cell lines Muscarinic Acetylcholine Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human CHRM2 Stable Cell Line

    [CAT#: S01YF-0923-PY128]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX635 Magic™ Rat CHRM2 in Vitro Calcium Flux Assay Rat CHO-K1-Gα16 Calcium Flux Assay

    Product Information

    Target Protein
    CHRM2
    Target Family
    Muscarinic Acetylcholine Family
    Target Protein Species
    Human
    Host Cell Type
    U87MG;A172;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research;Pain and Addiction Research
    Related Diseases
    Depressive Disorder;Drug Dependence
    Gene ID
    Human: 1129
    UniProt ID
    Human: P08172

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CHRM2, encoding the muscarinic acetylcholine receptor M2, has been extensively studied for its role in various physiological processes. In the context of cancer, CHRM2 has been identified as a potential prognostic marker in hepatocellular carcinoma, with its involvement in essential tumor-promoting pathways. Furthermore, variations in CHRM2 have been associated with tardive dyskinesia in schizophrenia, suggesting its potential role in neuropsychiatric disorders. The receptor's involvement in cognitive operations also underscores its significance in neurological research.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CHRM2 Stable Cell Line (S01YF-0923-PY128). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Rebecca (Verified Customer)

    How is CHRM2 associated with tardive dyskinesia in schizophrenia patients? Aug 13 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Variations in the CHRM2 gene have been associated with tardive dyskinesia in schizophrenia, although the association may be influenced by other concomitant factors. Aug 13 2020

    chat Cynthia (Verified Customer)

    What role does CHRM2 play in the transition from acute to chronic neuropathic pain? Jan 02 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CHRM2 is involved in the acute-to-chronic neuropathic pain transition, with REST up-regulation in DRG neurons playing a crucial role in the transcriptional repression of CHRM2 in neuropathic pain. Jan 02 2022

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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