CHRM2
A wider family of G protein-coupled receptors includes the muscarinic cholinergic receptors. Acetylcholine binding to these receptors determines their functional variety, which includes physiological reactions including adenylate cyclase inhibition, phosphoinositide degradation, and potassium channel mediation. Numerous cholinergic effects on the central and peripheral nervous systems are influenced by muscarinic receptors. The mediation of bradycardia and a decline in cardiac contractility is mediated by the muscarinic cholinergic receptor 2.
| Full Name | Cholinergic receptor muscarinic 2 |
| Gene ID | Human: 1129 Mouse: 243764 Rat: 81645 Monkey: 714780 |
| UniProt ID | Human: P08172 Mouse: Q9ERZ4 Rat: P10980 Monkey: Q4R7Y4 |
| Alternative Names | HM2; muscarinic acetylcholine receptor M2; 7TM receptor; acetylcholine receptor, muscarinic 2; muscarinic M2 receptor; CHRM2; Cholinergic receptor muscarinic 2 |
Product List
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Magic™ Human CHRM2 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX297]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CHRM2 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human CHRM2 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX298]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CHRM2 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human CHRM2 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX5]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CHRM2 Target Family: Acetylcholine (Muscarinic) receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human CHRM2 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX107]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CHRM2 Target Family: Muscarinic Acetylcholine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human M2 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX8]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: M2 Target Family: Acetylcholine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
mProX™ Human CHRM2 Stable Cell Line
[CAT#: S01YF-0923-PY128]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CHRM2 Target Family: Muscarinic Acetylcholine Family Target Protein Species: Human Host Cell Type: U87MG;A172;CHO-K1;HEK293
Magic™ Human FLAG tagged CHRM2 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX458]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CHRM2 Target Family: Muscarinic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
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