mProX™ Human CELSR2 Stable Cell Line
[CAT#: S01YF-0223-KX6]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
CELSR2 is a member of the flamingo subfamily, which is a branch of the cadherin superfamily. It is a cadherin EGF LAG seven-pass G-type receptor. Nonclassical cadherins, a fraction of which does not interact with catenins, make up the flamingo subfamily. Studies on the CELSR2 gene are currently mostly concentrated on the processes of serum cholesterol metabolism, coronary artery disease, and diseases of the nervous system. Additionally, some cancers have been discovered to include CELSR2 functionalities. In comparison to benign epithelial cells, breast cancer cells showed enhanced cytoplasmic staining for CELSR2 and inhibitor of growth 4 (ING4), indicating a potential role for both genes in the pathogenesis of human mammary neoplasia. Methylation of CELSR2 has been demonstrated to be crucial for carcinogenesis and tumor development in prostate cancer. The customized CELSR2 stable cell line can be employed in the signaling pathway researches, as well as other applications.
Protocols
Please visit our protocols page.
Customer Reviews
Kevin
The CELSR2 cell line is suitable for our high-throughput drug screening.
Feb 18 2023
Verified Customer
Robert
Very easy to use for drug screening and fast turnaround too.
Oct 22 2022
Verified Customer
FAQ
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