CELSR2
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
| Full Name | Cadherin EGF LAG seven-pass G-type receptor 2 |
| Gene ID | Human: 1952 Mouse: 53883 Rat: 83465 Monkey: 700893 |
| UniProt ID | Human: Q9HCU4 Mouse: Q9R0M0 Rat: Q9QYP2 Monkey: F6SGH4 |
| Alternative Names | EGFL2; MEGF3; ADGRC2; CDHF10; Flamingo1; cadherin EGF LAG seven-pass G-type receptor 2; EGF-like protein 2 EGF-like-domain, multiple 2; adhesion G protein-coupled receptor C2; cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); epidermal growth factor-like 2; epidermal growth factor-like protein 2; flamingo homolog 3; multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; CELSR2; Cadherin EGF LAG seven-pass G-type receptor 2 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CELSR2 Target Family: Cadherin Family Target Protein Species: Human Host Cell Type: L02; CHO-K1; HEK293
