mProX™ Human CCRL2 Stable Cell Line

[CAT#: S01YF-0923-PY54]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

CCRL2

Target Family

Chemokine Family

Target Protein Species

Human

Host Cell Type

MDS92;MDS-L;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Immunology Research

Related Diseases

Rheumatoid Arthritis ;Arthritis

Gene ID

Human: 9034

UniProt ID

Human: O00421

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Ronald (Verified Customer)

How does CCRL2 contribute to antitumor T-cell immunity? Sep 26 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

CCRL2 has been found to activate immunostimulatory macrophages, thereby amplifying antitumor T-cell responses and promoting tumor rejection. This suggests that CCRL2 could be a potential biomarker and therapeutic target for cancer immunotherapy. Sep 26 2020

chat Michelle (Verified Customer)

What role does CCRL2 play in myelodysplastic syndrome and secondary acute myeloid leukemia? Apr 25 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

CCRL2 is up-regulated in primitive cells from patients with myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia (sAML). It acts as a growth mediator for MDS/sAML cells, partially through the JAK2/STAT signaling pathway. Apr 25 2020

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