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    Family stable cell lines Cholecystokinin Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human CCKAR Stable Cell Line

    [CAT#: S01YF-0923-PY55]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    CCKAR
    Target Family
    Cholecystokinin Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research;Digestive and Renal Research
    Related Diseases
    Panic Disorder ;Gallbladder Disease
    Gene ID
    Human: 886
    UniProt ID
    Human: P32238

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Cholecystokinin A receptor (CCKAR) is a G-protein-coupled receptor that binds the peptide hormone cholecystokinin (CCK). This receptor plays a vital role in various physiological processes, including the regulation of pancreatic enzyme secretion and gallbladder contraction. In the scientific research landscape, CCKAR has been associated with metabolic processes and the regulation of food intake. Recent studies have also highlighted its potential role in growth in poultry, suggesting its influence on food intake and growth patterns. Furthermore, its involvement in metabolic hormone regulation and potential implications in conditions like obesity-associated asthma underscores the importance of CCKAR in metabolic research.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat Jennifer (Verified Customer)

    How does CCKAR influence obesity-induced airway hyperresponsiveness? Jul 26 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The metabolic hormone cholecystokinin (CCK) and its receptor CCKAR play a significant role in airway smooth muscle cells. Antagonizing CCKAR in the lung can abolish obesity-induced airway hyperresponsiveness, suggesting a potential therapeutic strategy for obese asthmatics. Jul 26 2020

    chat Kimberly (Verified Customer)

    What is the association between CCKAR and body weight in chickens? Sep 16 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Research has identified a key region in the CCKAR gene that harbors functional variants affecting the growth of chickens. This suggests that the CCKAR gene plays a role in determining body weight in poultry. Sep 16 2022

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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