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    mProX™ Human CASP6 Stable Cell Line

    [CAT#: S01YF-0923-PY115]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    CASP6
    Target Family
    Melanin-concentrating Hormone Family
    Target Protein Species
    Human
    Host Cell Type
    THP-1;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research;Cancer Research
    Related Diseases
    Huntington Disease;Colorectal Cancer
    Gene ID
    Human: 839
    UniProt ID
    Human: P55212

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CASP6, also known as Caspase-6, is an essential enzyme involved in the execution phase of cell apoptosis. In the realm of scientific research, CASP6 has been extensively studied for its role in neurodegenerative diseases, particularly Alzheimer's disease. Aberrant activation of CASP6 has been linked to the cleavage of essential neuronal proteins, leading to axonal degeneration and neuronal death. This enzyme is not only a marker of early neuronal dysfunction but also a potential therapeutic target. Inhibiting CASP6 activity could provide a novel approach to treat neurodegenerative disorders and prevent cognitive decline.

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    FAQ

    chat Kevin (Verified Customer)

    Can propofol mitigate inflammatory damage in ischemic brain injury? Dec 12 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, propofol can attenuate inflammatory damage by inhibiting the NLRP1-Casp1-Casp6 signaling pathway, offering a potential strategy for neuroprotection in stroke cases. Dec 12 2021

    chat Melissa (Verified Customer)

    What role does CASP6 play in pancreatic adenocarcinoma? Mar 30 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The knockdown of CASP6 can significantly inhibit the proliferation, migration, and invasion abilities of PANC-1 cells in vitro, indicating its crucial role in the progression of pancreatic adenocarcinoma. Mar 30 2020

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    • mProX™ Human CASP6 Stable Cell Line (CAT#: S01YF-0923-PY115)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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