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CASP6

A member of the cysteine-aspartic acid protease (caspase) family of enzymes is encoded by this gene. The execution phase of cell apoptosis depends heavily on the sequential activation of caspases. Caspases are inactive proenzymes that go through proteolytic processing to produce two subunits, large and small, which dimerize to form the active enzyme. This protein is hypothesized to work as a downstream enzyme in the caspase activation cascade and is broken down by caspases 7, 8, and 10.

Full Name Caspase 6
Gene ID Human: 839
Mouse: 12368
Rat: 83584
Monkey: 698788
UniProt ID Human: P55212
Mouse: O08738
Rat: O35397
Monkey: F7GYT8
Alternative Names MCH2; CSP-6; apoptotic protease MCH-2; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease

Product List

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Product Category:
Membranes
Target Protein: MCH2 Target Family: Melanin-Concentrating Hormone Target Protein Species: Human Host Cell Type: CHO dhfr- Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CASP6 Target Family: Melanin-Concentrating Hormone Target Protein Species: Human Host Cell Type: CHO dhfr- Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: CASP6 Target Family: Melanin-concentrating Hormone Family Target Protein Species: Human Host Cell Type: THP-1;CHO-K1;HEK293 Assay Types: Biological assays
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