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    mProX™ Human CACNA1D Stable Cell Line

    [CAT#: S01YF-1123-KX10]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    CACNA1D
    Target Family
    Voltage Gated Calcium Channel
    Target Protein Species
    Human
    Host Cell Type
    tsA-201; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    Auditory and Otology Research; CNS Research
    Related Diseases
    Primary Aldosteronism; Seizures; Deafness
    Gene ID
    776
    UniProt ID
    Q01668

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The CACNA1D gene is a member of a group of genes that give instructions on how to create calcium channels. One component of a calcium channel called CaV1.3, the alpha-1 subunit, is made according to instructions from the CACNA1D gene. This component creates the pore (hole) that allows calcium ions to pass through. Although CaV1.3 channels are present in many different types of cells, the adrenal glands-small hormone-producing glands situated on top of each kidney-play a special role for them. The production of the hormone aldosterone, which lowers blood pressure by ensuring that the body's salt and fluid levels are balanced, is thought to be regulated in part by the calcium influx through CaV1.3 channels in the adrenal glands. The inner ear, heart, and brain all have CaV1.3 channels. The customized CACNA1D stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    Customer Reviews

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    FAQ

    chat Michelle (Verified Customer)

    Can CACNA1D polymorphisms affect emotional memory components? Apr 25 2020

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Yes, certain CACNA1D polymorphisms have been linked to influencing components of human emotional memory, particularly in relation to rewarding expressions. Apr 25 2020

    chat Jennifer (Verified Customer)

    How does CACNA1D influence physiological processes? Jul 26 2020

    chat Sherry Smith (Creative Biolabs Scientific Support)

    CACNA1D is involved in the regulation of neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Jul 26 2020

    Related Products by Target
    • mProX™ Human CACNA1D Stable Cell Line (CAT#: S01YF-1123-KX10)
    • Magic™ mPro Human CACNA1D/CACNB3/CACNA2D1 Cell Line (CAT#: S01YF-1122-KX70)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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