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    mProX™ Human CACNA1C Stable Cell Line

    [CAT#: S01YF-1123-KX9]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Ion Channel Cell Lines

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    Product Information

    Target Protein
    CACNA1C
    Target Family
    Voltage Gated Calcium Channel
    Target Protein Species
    Human
    Host Cell Type
    Neuro2A; CHO-K1; HEK293
    Target Classification
    Ion Channel Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Timothy Syndrome; Long Qt Syndrome
    Gene ID
    775
    UniProt ID
    Q13936

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Making one of the calcium channels is controlled by the CACNA1C gene. CaV1.2 is the name of the calcium channel that the CACNA1C gene produces. Although these channels can be found in many different cell types, it appears that cardiomyocytes and brain neurons in particular rely on them for proper operation. CaV1.2 channels in the heart regulate the influx of calcium ions into cardiomyocytes at particular intervals during each heartbeat. To keep the heart functioning normally, the length of time the channels are open and closed is controlled. CaV1.2 channels are believed to play a role in memory, the fear response, and the quick transmission of nerve signals in the brain. The customized CACNA1C stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

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    Customer Reviews

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    FAQ

    chat Sharon (Verified Customer)

    Is CACNA1C involved in cardiac conduction disorders? Feb 09 2022

    chat Sherry Smith (Creative Biolabs Scientific Support)

    Yes, polymorphisms of the CACNA1C gene have been associated with primary cardiac conduction disorders. Feb 09 2022

    chat Ronald (Verified Customer)

    How does CACNA1C influence memory related to affective information? Sep 26 2020

    chat Sherry Smith (Creative Biolabs Scientific Support)

    CACNA1C has been studied for its role in the production of false memories for affective information. Sep 26 2020

    Related Products by Target
    • mProX™ Human CACNA1C Stable Cell Line (CAT#: S01YF-1123-KX9)
    • Magic™ mPro Human CACNA1C/CACNB2/CACNA2D1 Cell Line (CAT#: S01YF-1122-KX69)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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