CACNA1C
An alpha-1 subunit of a voltage-dependent calcium channel is encoded by this gene. Upon membrane polarization, calcium ions enter the cell through calcium channels. The pore via which ions enter the cell is formed by the 24 transmembrane segments that make up the alpha-1 subunit. Alpha-1, alpha-2/delta, beta, and gamma subunits make up the calcium channel complex in a 1:1:1:1 ratio. Each of these proteins has different isoforms that are either encoded by distinct genes or the product of alternative transcript splicing. This gene produces a protein that binds to and inhibits dihydropyridine.
| Full Name | Calcium voltage-gated channel subunit alpha1 C |
| Gene ID | Human: 775 Mouse: 12288 Rat: 24239 Monkey: 721721 |
| UniProt ID | Human: Q13936 Mouse: Q01815 Rat: P22002 Monkey: F7HT59 |
| Alternative Names | TS; LQT8; CACH2; CACN2; CaV1.2; CCHL1A1; CACNL1A1; TS. LQT8; voltage-dependent L-type calcium channel subunit alpha-1C; DHPR, alpha-1 subunit; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; voltage-dependent L-type Ca2+ channel alpha 1 subunit; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*; CACNA1C; Calcium voltage-gated channel subunit alpha1 C |
Product List
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Magic™ mPro Human CACNA1C/CACNB2/CACNA2D1 Cell Line
[CAT#: S01YF-1122-KX69]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CACNA1C/CACNB2/CACNA2D1 Target Family: Voltage Gated Calcium Channel Target Protein Species: Human
mProX™ Human CACNA1C Stable Cell Line
[CAT#: S01YF-1123-KX9]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CACNA1C Target Family: Voltage Gated Calcium Channel Target Protein Species: Human Host Cell Type: Neuro2A; CHO-K1; HEK293
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