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    mProX™ Human C3AR1 Stable Cell Line

    [CAT#: S01YF-0923-PY14]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    C3AR1
    Target Family
    Anaphylatoxin Family
    Target Protein Species
    Mouse
    Host Cell Type
    3T3-L1;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research
    Related Diseases
    Hemolytic Uremic Syndrome, Atypical 1;Complement Component 3 Deficiency
    Gene ID
    Mouse: 12267
    UniProt ID
    Mouse: O09047

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The C3AR1 gene, encoding the C3a receptor 1, has been a subject of significant interest in the realm of scientific research. This receptor is a part of the complement system and plays a pivotal role in various physiological and pathological processes. Recent studies have highlighted the association of C3AR1 with lupus nephritis, where mRNA expression levels of glomerular C3AR1 have been identified in specific gene sets and signaling pathways, including interferon signaling. Furthermore, the C3AR1 gene has been linked to Alzheimer's disease, suggesting a potential role in the progression of the disease. Another intriguing study revealed the involvement of C3AR1 in the progression of septic shock, identifying CD63 and C3AR1 as significant hub genes. Additionally, research has indicated that C3AR1 mRNA could serve as a therapeutic target in osteosarcoma, associating it with the tumor microenvironment and macrophage infiltration. In essence, the C3AR1 gene has diverse applications in scientific research, ranging from autoimmune disorders to neurodegenerative diseases and cancer.

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    Please visit our protocols page.

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    FAQ

    chat Kevin (Verified Customer)

    Is C3AR1 only associated with ovarian cancer? May 18 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    No, while C3AR1 is associated with the prognosis and immune cell infiltration of ovarian cancer, it has also been linked to other conditions such as lupus nephritis and endometriosis-driven tumorigenesis. May 18 2022

    chat Anthony (Verified Customer)

    Does C3AR1 play a role in the immune response of the tumor microenvironment? Apr 02 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, C3AR1 is suggested to be a promising immunotherapeutic target due to its association with immune cell infiltration in the tumor microenvironment. Apr 02 2020

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    • Magic™ Human C3AR1 CHO-K1 Cell Line, Binding and Functional Assay (CAT#: S01YF-1222-KX233)
    • mProX™ Human C3AR1 Stable Cell Line (CAT#: S01YF-0923-PY14)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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