mProX™ Human BRS3 Stable Cell Line

[CAT#: S01YF-0923-PY23]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX237	Magic™ Mouse BRS3 in Vitro Calcium Flux Assay	Mouse	CHO-K1-Gα16	Calcium Flux Assay
S01YF-1122-KX238	Magic™ Rat BRS3 in Vitro Calcium Flux Assay	Rat	CHO-K1-Gα16	Calcium Flux Assay

Product Information

Target Protein

BRS3

Target Family

Bombesin Family

Target Protein Species

Rat

Host Cell Type

INS-1 832/3;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Cancer Research

Related Diseases

Brugada Syndrome 4;Lung Cancer

Gene ID

Rat: 260319

UniProt ID

Rat: Q8K418

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

BRS3, or Bombesin Receptor Subtype-3, is a G-protein coupled receptor that has been the subject of various scientific investigations. One of the primary areas of interest is its role in the regulation of body temperature, energy expenditure, and heart rate. Research has shown that Brs3 neurons in the mouse dorsomedial hypothalamus play a pivotal role in these physiological processes. However, it's noteworthy that these neurons do not significantly influence food intake. This distinction is crucial as it helps differentiate the specific functions of BRS3 from other related receptors. The understanding of BRS3's role in these physiological processes can pave the way for potential therapeutic interventions, especially in conditions related to energy metabolism and thermoregulation. As research continues, the intricate roles and potential applications of BRS3 in scientific research are expected to be further elucidated.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Melissa (Verified Customer)

What is the significance of BRS3 in scientific research? Mar 15 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

BRS3 is a gene that encodes for a G-protein coupled receptor, which plays a role in various physiological processes. It has been studied in the context of energy homeostasis, thermogenesis, and feeding behavior. Mar 15 2022

chat Deborah (Verified Customer)

Are there any known associations between BRS3 and diseases or disorders? Nov 20 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

Research has indicated that mutations in the BRS3 gene can lead to rare genetic syndromes characterized by obesity, hyperphagia, and other endocrine abnormalities. Nov 20 2020

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