BRS3
A G protein-coupled membrane receptor called BRS3 binds peptides with bombesin-like properties. The physiological effects of this binding include the modulation of metabolic rate, glucose metabolism, and hypertension. This binding results in the activation of a phosphatidylinositol-calcium second messenger pathway. BRS3-related illnesses include Jejunal Somatostatinoma and Brugada Syndrome 4 (BRS4). Development Endothelin-1/EDNRA transactivation of EGFR and Class A/1 are two of its associated pathways (Rhodopsin-like receptors). Bombesin receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.
Full Name | Bombesin receptor subtype 3 |
Gene ID | Human: 680 Mouse: 12209 Rat: 260319 Monkey: 574261 |
UniProt ID | Human: P32247 Mouse: O54798 Rat: Q8K418 Monkey: Q6H2Y3 |
Alternative Names | BB3; BB3R; BBR3; bombesin receptor subtype-3; BRS-3; G-protein coupled receptor; bombesin like receptor 3; BRS3; Bombesin receptor subtype 3 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BRS3 Target Family: Bombesin Family Target Protein Species: Rat Host Cell Type: INS-1 832/3;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BRS3 Target Family: Bombesin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay