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BRS3

A G protein-coupled membrane receptor called BRS3 binds peptides with bombesin-like properties. The physiological effects of this binding include the modulation of metabolic rate, glucose metabolism, and hypertension. This binding results in the activation of a phosphatidylinositol-calcium second messenger pathway. BRS3-related illnesses include Jejunal Somatostatinoma and Brugada Syndrome 4 (BRS4). Development Endothelin-1/EDNRA transactivation of EGFR and Class A/1 are two of its associated pathways (Rhodopsin-like receptors). Bombesin receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.

Full Name Bombesin receptor subtype 3
Gene ID Human: 680
Mouse: 12209
Rat: 260319
Monkey: 574261
UniProt ID Human: P32247
Mouse: O54798
Rat: Q8K418
Monkey: Q6H2Y3
Alternative Names BB3; BB3R; BBR3; bombesin receptor subtype-3; BRS-3; G-protein coupled receptor; bombesin like receptor 3; BRS3; Bombesin receptor subtype 3

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: BRS3 Target Family: Bombesin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: BRS3 Target Family: Bombesin Family Target Protein Species: Rat Host Cell Type: INS-1 832/3;CHO-K1;HEK293
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