mProX™ Human BDKRB2 Stable Cell Line

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The Bradykinin Receptor B2 (BDKRB2) is another receptor that has garnered significant attention in the scientific community. It is primarily known for its role in mediating the effects of bradykinin, a potent vasodilator. The importance of BDKRB2 is underscored by its involvement in various physiological processes, including pain sensation, blood pressure regulation, and inflammation. Research has shown that antagonists targeting BDKRB2 can have potential therapeutic benefits in conditions like pain and inflammation. Moreover, the interaction between BDKRB2 and the bradykinin system has been explored in the context of stress and anxiety. Studies suggest that the bradykinin system, through B2 receptor-mediated effects, can modulate various stress responses. However, systemic antagonists of B2 receptors have shown varied results in terms of their anxiolytic effects. Additionally, genetic studies on BDKRB2 have provided insights into its potential role in determining the responsiveness to certain drugs, especially those related to cardiovascular health. The diverse roles of BDKRB2 make it a promising target for therapeutic interventions and a subject of ongoing research in various scientific domains.