mProX™ Human AGTR2 Stable Cell Line

[CAT#: S01YF-0923-PY18]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Bulk Quote

Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX220	Magic™ Dog AGTR2 in Vitro Radioligand Binding Assay	Dog	CHO-K1	Radioligand Binding Assay

Product Information

Target Protein

AGTR2

Target Family

Anaphylatoxin Family

Target Protein Species

Human

Host Cell Type

HSC3;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research

Related Diseases

Non-Syndromic X-Linked Intellectual Disability;Obstructive Nephropathy

Gene ID

Human: 186

UniProt ID

Human: P50052

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The AGTR2 gene, encoding the angiotensin II receptor type 2, has been a subject of significant scientific exploration, especially in the context of its physiological and pathological roles. Recent research has unveiled the potential of AGTR2 in the context of viral infections, particularly its interaction with SARS-CoV-2. A study highlighted that AGTR2 has a high tissue specificity in the lungs and may serve as a potential entry point for SARS-CoV-2 into human cells. Furthermore, another investigation revealed a borderline association of the AGTR2 genotype with COVID-19 retinopathy in males, suggesting its potential role in the ocular manifestations of the disease. Additionally, AGTR2 has been associated with cycling performance, where specific gene polymorphisms were linked to power/sprint performance in athletes. In essence, AGTR2 has diverse applications in scientific research, ranging from viral infections to athletic performance.

Protocols

Please visit our protocols page.

Customer Reviews

There are currently no Customer reviews or questions for mProX™ Human AGTR2 Stable Cell Line (S01YF-0923-PY18). Click the button above to contact us or submit your feedback about this product.

FAQ

chat Emily (Verified Customer)

Is AGTR2's role limited to cardiovascular health? Mar 20 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

No, AGTR2 has diverse roles, including its involvement in collagen accumulation in atherosclerotic plaque and potential implications in cancer. Mar 20 2021

chat Rebecca (Verified Customer)

Can overexpression of AGTR2 impact collagen levels in the body? May 26 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

Yes, overexpression of AGTR2 has been shown to reduce collagen accumulation in atherosclerotic regions. May 26 2021

Related Products by Target

Online Inquiry

Thank you for your interest in mProX™ Human AGTR2 Stable Cell Line. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

Estimated delivery time for your area;
Product sample or exclusive offer;
In-lab demonstration;

Creative Biolabs does not share your email address with third parties. Creative Biolabs will use your email address to confirm your identity and send you transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.