mProX™ Human ADRA2B Stable Cell Line

Product Information

Target Protein

ADRA2B

Target Family

Adrenergic Family

Target Protein Species

Human

Host Cell Type

THP-1;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

CNS Research

Related Diseases

Familial Adult Myoclonic Epilepsy;Mild Cognitive Impairment

Gene ID

Human: 151

UniProt ID

Human: P18089

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The ADRA2B gene has been a subject of interest in various scientific studies. One of the notable findings is its association with the environmental levels of carbaryl, which seems to impair zebrafish larvae behavior. Research suggests that antagonism of ADRA2B leads to adverse outcomes in zebrafish larvae exposed to environmentally relevant levels of carbaryl. Another study delves into the biogenic amine receptors, specifically focusing on the ADRA2B and its implications in mental disorders. The study emphasizes the evolutionary analysis and structural features of the ADRA2B, drawing conclusions about its functionality. Furthermore, ADRA2B has been linked to the cardiac conduction system (CCS) disease, which disrupts cardiac rhythm. Genome-wide association studies have identified ADRA2B as a significant locus associated with adult human CCS function. In summary, ADRA2B plays a pivotal role in various physiological processes, from mental health to cardiac functions, making it a crucial gene for scientific exploration.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Nancy (Verified Customer)

Is ADRA2B involved in cardiac conduction disorders? Jun 26 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

Yes, polymorphisms of the ADRA2B gene have been associated with primary cardiac conduction disorders. Jun 26 2022

chat Sarah (Verified Customer)

How does ADRA2B influence memory related to affective information? Mar 24 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

ADRA2B has been studied for its role in the production of false memories for affective information, suggesting that higher levels of noradrenaline in certain genotypes may enhance short-term consolidation of negative information. Mar 24 2022

chat Thomas (Verified Customer)

Can ADRA2B polymorphisms affect emotional memory components? Mar 18 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

Yes, certain ADRA2B polymorphisms have been linked to influencing components of human emotional memory, particularly in relation to rewarding expressions. Mar 18 2023

mProX™ Human ADRA2B Stable Cell Line

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