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    mProX™ Human ADRA2A Stable Cell Line

    [CAT#: S01YF-0923-PY8]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    ADRA2A
    Target Family
    Adrenergic Family
    Target Protein Species
    Mouse
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Gilles De La Tourette Syndrome;Motion Sickness
    Gene ID
    Mouse: 11551
    UniProt ID
    Mouse: Q01338

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The α2A-adrenergic receptor, ADRA2A, has been extensively studied in various scientific contexts, especially in relation to neurotransmission and therapeutic responses. A recent study found that knocking down Adra2a in diabetic adipose-derived stem cells enhanced the secretion of growth factors, accelerating wound healing, offering a potential therapeutic strategy for diabetic wounds. Additionally, genetic polymorphisms in ADRA2A have been associated with differential responses to dexmedetomidine, a sedative used in pediatric and cardiovascular intensive care units. In the context of Raynaud's phenomenon, a condition characterized by vasospasms in response to cold or stress, a genome-wide association study identified ADRA2A as a novel risk gene, emphasizing its role in hypersensitivity to catecholamine-induced vasospasms. These studies highlight the diverse roles of ADRA2A in various physiological and pathological processes, emphasizing its significance in scientific research and potential therapeutic applications.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human ADRA2A Stable Cell Line (S01YF-0923-PY8). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Kathleen (Verified Customer)

    What is the significance of ADRA2A in motion sickness? Oct 16 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Polymorphisms in ADRA2A have been linked to susceptibility to motion sickness-induced vomiting. Oct 16 2022

    chat Gary (Verified Customer)

    Can ADRA2A polymorphisms influence birth weight? Dec 06 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Yes, certain ADRA2A polymorphisms have been emphasized in determining birth weight and maternal weight gain during pregnancy. Dec 06 2020

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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