Human TLR7 Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX105]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Lentivirus
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order lentivirus expressed human TLR7.
Target Protein
TLR7
Target Classificationp
Immune Checkpoint
Target Family
Immune Checkpoint
Target Protein Species
Human
Protein Tag
Based on specific requirements (Flag, StrepII, His, etc.)
Buffer
HBSS
Titer
≧1.00E+8 TU/mL
Transfer Plasmid Backbone
pCDH or specific requirements
Size
100 uL*10 vials, 1 mL
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Target Research Area
Autoimmune Research; Immunology Research
Related Diseases
mmunodeficiency; Systemic Lupus Erythematosus
Quality Control
Titer Determination Method
RT-qPCR
Sterility Testing
Negative
Mycoplasma Testing
Negative
Transfection Efficiency
Positive (if EGFP is included in the transfer plasmid)
Endotoxin Level
Based on specific requirements
Product Properties
Application
Stable cell line generation; Protein expression; Biochemical assays
Safety Notes
Since the HIV genes are expressed from packaging plasmids devoid of the packing signal, none of the HIV genes will be expressed in the transduced cells. The pseudotyped lentiviruses need to be used in a Biosafety Level 2 facility even if they are replication-incompetent.
Shipping
Dry ice
Storage
Store at -80°C and avoid repeated freeze-thaw cycles.
Target
Full Name
Toll-like receptor 7
Introduction
Enables siRNA binding activity and single-stranded RNA binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; response to virus; and toll-like receptor 7 signaling pathway. Acts upstream of or within positive regulation of interleukin-6 production and regulation of protein phosphorylation. Located in cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Is expressed in brain and liver. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in COVID-19 and X-Linked immunodeficiency 74. Orthologous to human TLR7 (toll like receptor 7).
Alternative Names
TLR7; toll-like receptor 7
Gene ID
UniProt ID
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